mark, seal, sign
An assignation is a secret meeting between two people who are usually lovers.
When you consign someone into another's care, you sign them over or entrust them to that person's protection.
A designation is a name, label, or mark that something is given in order to identify it.
A feeling of resignation is one of submission, acceptance without protest, or an unresisting attitude.
Something that is significant is important or meaningful.
When you assign something to someone, you give them a job or a task to do.
When you design something, you prepare, plan, or create it.
A signal is a sound or action that has a special meaning to another person to whom it is given or sent.
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